Kanser tedavisinde etkisi yüksek, yan etki profili düşük olan akıllı moleküller ve immünoterapi ilaçlarının önemli bir kısmı Türkiye’de SGK’nın ödeme kapsamında değil. Hastanın hem yaşam kalitesini arttıran hem de ömrünü uzatan Sağlık Bakanlığı onaylı ilaçlar piyasada var ancak geri ödeme listesinde olmadığı için çok sayıda hasta bu ilaçlardan yararlanamıyor, çünkü maliyetleri çok yüksek. Yeni ve pahalı kanser ilaçlarına erişimin sadece Türkiye’nin değil, tüm dünyanın sorunu olduğunu belirten onkologlar, bu durumun onkoloji literatürüne “finansal toksisite”, yani ekonomik yan etki şeklinde bir terim eklediğini söylüyor.
Kanser tedavisinde çok önemli avantaj sağlayan bazı akıllı molekül ve immünoterapi ilaçları SGK’nın geri ödeme kapsamında bulunmuyor. Bu nedenle çok sayıda hasta, kemoterapiden daha fazla yarar göreceği ve yan etki yükünden önemli oranda kurtulabileceği bu ilaçları alamıyor, alınamayan bu ilaçlar hastayı mağdur ediyor. çünkü bu ilaçlar çok pahalı
Örneğin meme kanserinde hormonal terapilerle akıllı moleküllerin beraber kullanılmasının etkinliği ve hastalık kontrolünü çok önemli oranda artırdığını belirten İç Hastalıkları ve Tıbbi Onkoloji Uzmanı Prof. Dr. Gökhan Demir, “Maalesef immünoterapi ajanlarının veya akıllı ilaçların önemli bir kısmını SGK karşılamıyor. Türkiye’de bu ilaçlar piyasada var, yani Sağlık Bakanlığı onay verdi ama geri ödeme kurumu geri ödemeye almadı. Bu nedenle birçok hastamız mağdur oluyor. Hasta, göz göre göre progrese oluyor, yani hastalığı ilerliyor ama bu akıllı ilaçları veremediğimiz için etkinliği onlardan daha az, yan etkileri ise daha fazla olan kemoterapi veriyoruz” dedi.
Doktor Gökhan Demir, etkin ama pahalı ilaçların onkoloji literatürüne bir terim de eklediğini söyledi: Finansal toksisite:
“Biz eskiden ilaçların hep vücuda yaptığı bir toksisiteden, bir yan etkiden söz ediyorduk, mide bulantısı, saç dökülmesi, halsizlik, iştahsızlık gibi. İşte bu toksisitenin yanına bir de finansal toksisite eklendi. Finansal toksisite bugün bütün dünyada konuşulan bir şey. Çünkü yeni çıkan ilaçlar, hedefe yönelik tedaviler ve akıllı moleküller, çok korkunç maliyetler oluşturuyor ve bu ilaçların uzun yıllar kullanılması finansal toksisiteyi daha fazla artırıyor. ABD başta olmak üzere birçok gelişmiş ülke bütçelerinde bu yeni kuşak ilaçlara nasıl bir pay ayıracakları konusunu tartışıyor.”
İstanbul Tabip Odası Başkanı ve Tıbbi Onkoloji Uzmanı Prof. Dr. Pınar Saip de finansal yan etki konusunda farkındalığın giderek arttığını, iş kaybı, çalışamama, tedaviye erişememe gibi konuların da “finansal toksisite” kapsamında olduğunu söyledi, “Finansal yan etkiyi önlemek kanser araştırmacılarının ve sağlık sistemlerinin önemli görevlerinden olmalıdır. Finansal yan etkinin önlenmesi hem kanser kontrolünü hem de kanserde sağkalımı arttırır” ifadelerini kullandı.
Türk Tıbbi Onkoloji Derneği (TTOD) Yönetim Kurulu Üyesi ve Tıbbi Onkolog Prof. Dr. Mahmut Gümüş ise finansal toksisitenin sadece Türkiye’nin değil, tüm dünyanın sorunu olduğunu, her ülkede yeni ve pahalı ilaçlara erişimde sıkıntı yaşandığını söyledi, “Bu, öyle bir hal aldı ki artık Amerika veya Avrupa’da yapılan onkoloji kongrelerinde konuşmacılar ilacı anlatırken, ‘şu kadar etkilidir, şu kadar faydalıdır’ dedikten sonra bir de ilacın ekonomik maliyeti ile ilgili konuşma yapıyor” dedi.

“TÜRKİYE’DE MEME KANSERİ İLAÇLARINA ERİŞİMDE SORUN YAŞANIYOR”
Bazı meme kanseri ilaçlarına erişimde de sorun yaşandığını söyleyen Doktor Pınar Saip, “Bugün Türkiye'de meme kanseri tedavisinde ruhsatı olan ama geri ödemesi olmayan pahalı ilaçlar, hem geri ödemesi hem de ruhsatı olmayan pahalı ilaçlar ve bulunmayan ucuz ilaçlar sorunu yaşanıyor. Pahalı ilaçlar için Türkiye’de geri ödeme referans ülkelere bakılarak saptanıyor. En düşük referans ülke fiyatı belli bir yüzdeyle çarpılıyor, sabitlenmiş döviz kuruna göre belirleniyor. Bu fiyatlar da ilaç firmalarını tatmin etmiyor. Türkiye'de geri ödeme alabilmiş ilaçlar dünyanın diğer ülkelerine göre daha ucuz” ifadelerini kullandı.
“KANSER hastaların ekonomisini de etkiliyor.
Meme kanserinin tek bir hastalık olmadığını, hastalığın biyolojik türlerine ve evrelerine göre tedavilerinde farklılıklar bulunduğunu hatırlatan Onkolog Saip, “Maalesef meme kanserinin bazı türlerinde etkili olan yeni ilaçların bazıları ülkemizde geri ödeme kapsamında değil. Kanser hastalığı hasta ve ailesinde ekonomik sorunlara yol açar ve bu durum hastalığın seyri açısından risk faktörüdür. Ülkelerin gelir düzeyi, sağlığa ayırdığı bütçe ve finansal yan etki arasında ilişki vardır. Örneğin batı Avrupa’da meme kanseri daha sık olmasına rağmen orta Avrupa’da seyirleri daha kötüdür. Bu da bakım ve ilaca erişimin ne kadar önemli olduğunu göstermektedir. Yeni geliştirilen ilaç fiyatları giderek artmaktadır. Eski ilaçlar ise ucuz oldukları için piyasada bulunmamaktadır” diye konuştu.

Hiçbir şey insan yaşamından daha kutsal değildir
Prof. Demir, akıllı molekül ve immünoterapi ilaçlarının yüksek maliyeti için, “Evet, bu ilaçların çok yüksek bir ekonomik gideri var ama bir insanın hayatına kazandıracağımız bir günün hiçbir maddi bedeli yok. Bir açıdan da böyle bakmak gerekiyor. Bu, bütün dünyanın uğraştığı bir problem, Türkiye de finansal toksisite üzerinde çalışıyor” derken, Prof. Saip, “Ülkemizin Sağlık Bakanlığı ve SGK'sı özellikle hastalarımıza yarar sağlayacak ilaçlar konusunda elinden geleni yapmalı. Başka gereksiz harcamalardan kısılıp ömrü uzatacak, insan sağlığı için ihtiyaç olan alanlara mali destek sağlamalı” değerlendirmesinde bulundu.
“Klinik yarar baz alınmalı”
Her yeni geliştirilen ve pahalı olan ilacın, etkili olmayabileceğinin altını çizen Dr. Saip, “klinik yarar” vurgusu yaparak şunları söyledi:
“Bazı yeni geliştirilen ilaçlar klinik olarak anlamsız ama istatistiksel olarak anlamlı sonuçlar verebiliyor. Sadece yarar önemli değil, bu yararın ne kadar olduğu, ne pahasına olduğu da önemli. Bazı yeni ilaçların yan etkisi az, etkisi çoktur, bu tür ilaçlara ilgili uzmanlık derneklerinin görüşü alınarak onay verilmeli, geri ödeme sağlanmalı. Ama yararı net olmayan veya yan etkisi çok olan ilaçlarda geri ödeme sağlanmayabilir. Yani sadece istatistiksel yarar değil, klinik yarar baz alınmalı. İlaç araştırma ve geliştirme çok pahalı ve uzun bir süreç. Bu süreç sadece ilaç firmalarına bırakılmamalı. Bağımsız araştırmacılar devlet aracılığı ile desteklenerek daha ucuz ve etkili ilaçların geliştirilmesi, devlet politikası olmalı.”
“Herkes fedakarlık yaparsa ”
Klinik yarar konusunda, “En doğru hastayı, etkin olacağından yüzde yüz emin olduğumuz, en fazla fayda sağlayacağımız hastayı belirlemek ve bu ilaçları o hastaya vermek için bir takım politikalar geliştiriliyor” sözleriyle değerlendiren Prof. Demir’e göre, hem ilaç firmaları hem de geri ödeme kurumu biraz fedakarlık yapabilir ve çok sayıda hastanın hayatı kurtulabilir:
“Aslında ilaç firmaları ellerinden geleni yapıyor. Türkiye’de çıkardıkları fiyat, yurt dışındaki fiyattan neredeyse yüzde 30, yüzde 40 daha ucuz. Ayrıca insani erişim programları açıyorlar, yani bu konuda çok duyarsız değiller. Ama ilaç firmalarının da Türkiye’nin ve ülkelerin ekonomilerine göre fiyat belirlemeleri gerekir. Örneğin; insani erişim programları az sayıda hasta ile kısıtlı. Bunun pazarlığı yapılarak insani erişim programının kapsamı genişletilebilir.”
“Sağlık bakanlığı onkoloji dernekleri ile işbirliği yapmalı”
Finansal yan etkiyi önlemek için ilaç şirketleri dışında alternatif ilaç üretim yolları bulunması gerektiğini söyleyen Prof. Saip’in bu konudaki görüşü, “Akademi, SGK, Sağlık Bakanlığı ve Türk Tıbbi Onkoloji Derneği işbirliği yapmalı, klinik yararın büyüklüğüne göre geri ödeme politikaları uygulanmalı” şeklinde.
“EŞDEĞER VE BİYOBENZER İLAÇLARA AĞIRLIK VERİLMELİ”
Onkolojik ilaçlardaki ekonomik yan etkiyi azaltmak için çözüm odaklı düşünmek gerektiğini dile getiren TTOD Üyesi Prof. Gümüş’e göre, eşdeğer ve biyobenzer ilaçlara ağırlık verilmeli:

“Çözüm için atılacak adımlardan biri eşdeğer ilaçların geliştirilmesidir. Patent süreleri bittikten sonra eşdeğer ilaç üretilirse ilaç firmaları arasındaki rekabet sonucu fiyatlar düşecektir. İkincisi biyolojik ilaçlarda biyobenzer diye bir kavram var, bu da aynı şekilde patent sürelerinin bitmesiyle piyasaya yeni oyuncuların çıkmasını, benzer ilaçların üretilmesini ve ilaçların ucuzlamasını sağlıyor. Hem doktorlar hem de hastalar olarak bizim bunu desteklememiz lazım.”
“UCUZ İLAÇLAR SGK KAPSAMINDAN ÇIKARILSIN, KANSERE AYRILAN KAYNAK ARTIRILSIN”
Bu konuda yeni politikalar geliştirilmesi gerektiğine vurgu yapan Doktor Mahmut Gümüş, “Örneğin bazı ağrı kesici, mide veya vitamin ilacı gibi ucuz ilaçların SGK ödeme kapsamından çıkarılması, dolayısıyla kanser ilaçlarına daha fazla kaynak ayrılması söz konusu olabilir. Çünkü bu tür ilaçları toplumun büyük bir kısmı alabilir ama kanser ilaçlarını herkes alamaz” dedi.
“YENİ ÇIKAN HER İLACI ‘SGK ÖDESİN’ DEMEK SÜRDÜRÜLEBİLİR BİR ŞEY DEĞİL”
Bu tür önlemler alınarak, sağlığa ayrılan bütçe artırılarak hastaların bu ilaçlara daha kolay ulaşmalarını sağlamak için çaba gösterilmesi gerektiğini söyleyen Dr. Gümüş sözlerini, “Ama bunlar sürdürülebilir çözümler değil. Yani her yeni ilaç çıktığında ‘SGK ödesin’ demek sürdürülebilir bir şey değil. Gerçekten maliyetler o kadar fazla ki değil Türkiye’nin dünyanın gelişmiş ülkelerinin bile bunların üstesinden gelmesi mümkün değil. Ama bunun çok ciddi bir sorun olduğunu ve hastaları mağdur ettiğini kabul etmemiz lazım. Tabii ki israf yapılmasın, kaynaklar iyi yerlere harcansın ve sağlığa ayrılan pay artırılsın ama ülkenin de bir bütçesi var” şeklinde tamamladı.
Yorumlar
An early diagnosis,…
An early diagnosis, regardless of age, usually makes breast cancer more treatable.
Excellent health benefits are attainable when you <a href="https://blueboostsilden.com/ ">sildenafil citrate vs viagra</a> pills from these pharmacies
Because many animal bites are never reported, determining the exact incidence of animal bite wounds in the United States, let alone the world, is difficult.
Если вы искали где…
Если вы искали где отремонтировать сломаную технику, обратите внимание - <a href=https://barnaul.profi-teh-remont.ru>сервис центр в барнауле</a>
Если вы искали где…
Если вы искали где отремонтировать сломаную технику, обратите внимание - <a href=https://chelyabinsk.profi-teh-remont.ru>техпрофи</a>
Hide copyright information…
Hide copyright information Copyright dengue breakbone fever deng-i n.
Discover great offers you can use to <a href="https://bluetabletsilden.com/ ">sildenafil warnings</a> you can save even more when you get generic.
Many brain tumors can lead to death even with the best treatment.
ETZ Расстановки по…
ETZ Расстановки по Хеллингеру: эффективный метод. https://rasstanovkiural.ru
The only thing she has…
The only thing she has noticed is when I tried to reduce Abilify to 10 mg, she was shaky.
Go to <a href="https://bluetabletsilden.com/ ">goodrx sildenafil reviews</a> and save the money for other purchases.
Find out what causes it and how to feel better.
LDS Системно-семейные…
LDS Системно-семейные расстановки https://rasstanovkiural.ru
Профессиональный сервисный…
Профессиональный сервисный центр по ремонту бытовой техники с выездом на дом.
Мы предлагаем:<a href=https://remont-byttekhniki-ekb.ru>ремонт бытовой техники в екб</a>
Наши мастера оперативно устранят неисправности вашего устройства в сервисе или с выездом на дом!
Профессиональный сервисный…
Профессиональный сервисный центр по ремонту варочных панелей и индукционных плит.
Мы предлагаем: <a href=https://remont-varochnyh-paneley-clan.ru>профессиональный ремонт варочных панелей</a>
Наши мастера оперативно устранят неисправности вашего устройства в сервисе или с выездом на дом!
WFR Cемейные расстановки —…
WFR Cемейные расстановки — психотерапия или философия. https://rasstanovkiural.ru
<a href=https://remont…
<a href=https://remont-fotoapparatov-ink.ru>ремонт затвора фотоаппарата</a>
SHS Дизайн человека https:/…
SHS Дизайн человека https://rasschitat-dizayn-cheloveka-onlayn.ru Дизайн человека. 4/6 Дизайн человека.
IEZ Дизайн человека https:/…
IEZ Дизайн человека https://rasschitat-dizayn-cheloveka-onlayn.ru Дизайн человека. 2/4 Дизайн человека.
LFD Дизайн человека https:/…
LFD Дизайн человека https://vkl-design.ru Дизайн человека. 1/3 Дизайн человека.
Если вы искали где…
Если вы искали где отремонтировать сломаную технику, обратите внимание - <a href=https://chelyabinsk.profi-teh-remont.ru>сервисный центр в челябинске</a>
AMB Дизайн человека https:/…
AMB Дизайн человека https://humandesignplanet.ru Дизайн человека. 1/4 Дизайн человека.
CML Дизайн человека https:/…
CML Дизайн человека https://raschet-karty-dizayn-cheloveka.ru Дизайн человека. 5/1 Дизайн человека.
UII Дизайн человека https:/…
UII Дизайн человека https://vkl-design.ru Дизайн человека. 1/4 Дизайн человека.
Tags: Type 2, Diabetes…
Tags: Type 2, Diabetes Diagnosis, Prediabetes Post a comment Diabetes Symptom: Fatigue How It Feels "During the course of one week's time, I became a different person.
Check out how much you can save on <a href="https://lasixas365.com/ ">how much potassium with lasix</a> pills from this online portal
If you decide to avoid certain foods or drinks, make sure that your meals are still well-balanced and healthy.
Most fathers-to-be want very…
Most fathers-to-be want very much to be supportive, they just need instructions.
yourself familiar with requirements for pharmacies that sell <a href="https://lasixas365.com/ ">torsemide equivalent to lasix</a> when you are done analyzing cost savings to get the best
Smoking of other tobacco products, such as cigar and pipe smoking, is also associated with an increased risk of lung cancer.
Профессиональный сервисный…
Профессиональный сервисный центр по ремонту планшетов в Москве.
Мы предлагаем: <a href=https://remont-planshetov-ideo.ru>ремонт планшетов в москве</a>
Наши мастера оперативно устранят неисправности вашего устройства в сервисе или с выездом на дом!
CLF Дизайн человека https:/…
CLF Дизайн человека https://vkl-design.ru Дизайн человека. 5/2 Дизайн человека.
Профессиональный сервисный…
Профессиональный сервисный центр по ремонту бытовой техники с выездом на дом.
Мы предлагаем:<a href=https://remont-byttekhniki-nsk.ru>сервисные центры по ремонту техники в новосибирске</a>
Наши мастера оперативно устранят неисправности вашего устройства в сервисе или с выездом на дом!
In addition, estrogen…
In addition, estrogen replacement therapy often reduces testosterone levels, which may manifest as lack of energy and libido.
Has your <a href="https://bactriman24.com/ ">what is bactrim</a> at low prices
With LCIS, there are more abnormal cells in the lobule than with atypical hyperplasia.
The flu is caused by…
The flu is caused by influenza virus types A, B, and C.
Has your <a href="https://bactriman24.com/ ">bactrim ds for sinus infection</a> as they provide reliable reviews. Always get the best deal!
Plus I feel horrible Linda Thatcher January 12, 2015 at 1:33 pm - Reply I HAVE HAD UNUSUAL SPELLS OF FEELING EXTREMELY COLD INSIDE FOR NO APPARENT REASON.
Long-lost copy of the US…
Long-lost copy of the US Constitution, found in North Carolina filing cabinet, heads to auction
<a href=https://kraken19.com>kra2.gl</a>
Historical document appraiser and collector Seth Kaller spreads a broad sheet of paper across a desk. It’s in good enough condition that he can handle it, carefully, with clean, bare hands. There are just a few creases and tiny discolorations, even though it’s just a few weeks shy of 237 years old and has spent who knows how long inside a filing cabinet in North Carolina.
At the top of the first page are familiar words but in regular type instead of the sweeping Gothic script we’re used to seeing: “WE, the People …”
And the people will get a chance to bid for this copy of the US Constitution — the only of its type thought to be in private hands — at a sale by Brunk Auctions on Sept. 28 in Asheville, North Carolina.
https://kra8-at.net
kra4 cc
The minimum bid for the auction of $1 million has already been made. There is no minimum price that must be reached.
This copy was printed after the Constitutional Convention finished drafting the proposed framework of the nation’s government in 1787 and sent it to the Congress of the ineffective first American government under the Articles of Confederation, requesting they send it to the states to be ratified by the people.
It’s one of about 100 copies printed by the secretary of that Congress, Charles Thomson. Just eight are known to still exist and the other seven are publicly owned.
Actress Gemma Arterton says…
Actress Gemma Arterton says director tried to pressure her to do sex scene
<a href=https://kra13gl.com>kraken onion</a>
British actress Gemma Arterton has revealed that a director once tried to put pressure on her to film a sex scene, despite the fact that it wasn’t included in the script.
In an interview with British publication the Radio Times, released Tuesday, Arterton said that, whilst on set, the director - who hasn’t been named - instructed her and her co-star to film a sex scene on a bed.
“I said, ‘No, this scene was written for us to be off screen, so you just hear the noises,’” Arterton told the Radio Times. “I’d never have accepted the role if it was going to be filmed.”
https://kraken7-gl.com
kra13.gl
The actress said that she was pressured by the director to film the scene, but that she “flat out” refused to take part in it.
Had she been younger at the time, Arterton suggested that she might have been more concerned about being fired for refusing to film it.
“I only felt like I could say that because I was older,” she said.
“When I started acting, there was a lot of nudity – you were just expected to do it. When I was younger I played sexy characters, the girlfriend. As I’ve got older, that’s changed because I’m more successful and can choose the parts I want to play,” she said.
She praised the use of intimacy coordinators in film and television since the #MeToo movement, telling the magazine that “it’s a totally different landscape” now.
“Anything you’re not comfortable with is not going to happen. I’ve heard other actors that are like, ‘I loved it when there was no intimacy coordinator,’ but I definitely think it’s better,” she said.
Профессиональный сервисный…
Профессиональный сервисный центр по ремонту видео техники а именно видеокамер.
Мы предлагаем: <a href=https://remont-videokamer-dun.ru>ремонт камер</a>
Наши мастера оперативно устранят неисправности вашего устройства в сервисе или с выездом на дом!
Study shows how the pandemic…
Study shows how the pandemic may have affected teens’ brains
<a href=https://krak6.net>kra4 cc</a>
The pandemic’s effects on teenagers were profound — numerous studies have documented reports of issues with their mental health, social lives and more.
Now, a new study suggests those phenomena caused some adolescents’ brains to age much faster than they normally would — 4.2 years faster in girls and 1.4 years faster in boys on average, according to the study published Monday in the journal Proceedings of the National Academy of Sciences.
By being the first to contribute details on aging differences by sex, the study adds to the existing body of knowledge provided by two previous studies on the Covid-19 pandemic and accelerated brain aging among adolescents.
https://kra5.gl-kra5.cc
kra11.cc
“The findings are an important wake-up call about the fragility of the teenage brain,” said senior study author Dr. Patricia K. Kuhl, the Bezos Family Foundation Endowed Chair in Early Childhood Learning and codirector of the Institute for Learning and Brain Sciences at the University of Washington in Seattle, via email. “Teens need our support now more than ever.”
Significant socioemotional development occurs during adolescence, along with substantial changes to brain structure and function. The thickness of the cerebral cortex naturally peaks during childhood, steadily decreases throughout adolescence and continues to decrease through one’s lifespan, the authors wrote.
The researchers originally intended to track ordinary adolescent brain development over time, starting with MRIs the authors conducted on participants’ brains in 2018. They planned to follow up with them for another scan in 2020.
The pandemic delayed the second MRI by three to four years — when the 130 participants based in Washington state were between ages 12 and 20. The authors excluded adolescents who had been diagnosed with a developmental or psychiatric disorder or who were taking psychotropic medications.
Meet the artist transforming…
Meet the artist transforming tennis balls into furniture
<a href=https://blackspruta.com>btrhbfeojofxcpxuwnsp5h7h22htohw4btqegnxatocbkgd…;
In the last two years, tennis has taken over our closets (court-appropriate garb can be found everywhere from Skims to Miu Miu), our screens (who could forget Zendaya’s turn as the tennis protoge-turned-elite-coach Tashi Duncan in “Challengers”) and now — our living rooms.
At least that is the hope of Belgian eco-designer Mathilde Wittock, who fashions bespoke furniture from discarded tennis balls. Wittock’s sleek, modernist chaise longues are entirely cushionless — save for the padding of 500 precisely arranged tennis balls. Her one meter-long benches are similarly sparse, with some 270 balls being both stylish and structurally substantial.
https://blackspruta.com
bs2site2.at
“It takes around 24 different manufacturing steps to (make) a tennis ball, which is around five days. Then it has such a short lifespan,” Wittock told CNN in a video call from Brussels. “I was looking into tennis balls because I played tennis myself, so I know there is a lot of waste.”
Around 300 million tennis balls are produced each year — and almost all of them end up in landfills, taking over 400 years to decompose. The US Open, which ended at the weekend, goes through around 70,000 each year, with Wimbledon not far behind at 55,000. Wittock estimates the lifecycle of a ball stands at just nine games, depending on the level of tennis being played. “Even if they are contained in their box, if the box has been opened the gas inside the tennis balls will be released over time,” she said. “(Eventually) they will get flat and you’ll have to throw them away.”
<p><i>С выходом новой линии…
<p><i>С выходом новой линии мужских ароматов Esquire, мир парфюмерии обретает новые грани. Эти ароматы идеально подходят для мужчин, работающих в журналистике и медиа. Важно помнить, что перед лазерной эпиляцией лучше воздержаться от использования любых парфюмов, как советует Евгений Майер.</i></p><center><img alt="#ЛазернаяЭпиляция #ЕвгенийМайер #Ароматы #Esquire #Парфюм" src="https://pr-img.ru/2024/618/studija-lazernoj-epilyacii-mayer-1.jpg" style="display: block; margin-left: auto; margin-right: auto;max-width:100%;"></center><p>Коллекция включает четыре уникальные композиции, каждая из которых отражает богатое литературное наследие журнала и выдающихся авторов, таких как Ф. Скотт Фицжеральд и Э. Э. Каммингс. Главный редактор Esquire Майкл Себастьян отметил, что интерес читателей к мужской парфюмерии и уходу за собой стал стимулом для создания этой линии.</p><p>Ароматы, такие как American Novelist и Editor in Chief, призваны стать верными спутниками для представителей медиа и литераторов, подчеркивая их индивидуальность и стиль. Однако перед процедурами эпиляции диодным лазером, как подчеркивает создатель высококачественных <a href="https://mariamayer.ru/mayeridiod">диодных лазеров для эпиляции MAYER SAPPHIRE</a> и сооснователь студии "Mayer Studio" Евгений Майер, рекомендуется воздерживаться от использования любых парфюмов, туалетной воды и духов.</p><center><img alt="Евгений Майер - создатель устройства для лазерной эпиляции MAYER iDiod SAPPHIRE" src="https://pr-img.ru/2024/618/evgenij-mayer-sozdatel-lazera-dlja-epilyacii…; style="display: block; margin-left: auto; margin-right: auto;max-width:100%;"></center><p>Евгений Майер объясняет, что резкие запахи могут отвлечь косметолога от работы и снизить его концентрацию, что в свою очередь может привести к снижению эффективности процедуры или даже к травмам кожи. Он подчеркивает, что пациенты должны доверять косметологу самое ценное — свою кожу, поэтому важно обеспечить максимальный комфорт и безопасность во время сеанса.</p>
<a href=https://piarim.jofo.me/2280420.html?_ga=2.64506924.2004030985.172551346…;Евгений Майер - лазер для эпиляции</a>
Профессиональный сервисный…
Профессиональный сервисный центр по ремонту бытовой техники с выездом на дом.
Мы предлагаем: <a href=https://remont-byttekhniki-moskva.ru>ремонт бытовой техники в москве</a>
Наши мастера оперативно устранят неисправности вашего устройства в сервисе или с выездом на дом!
Scientists who discovered…
Scientists who discovered mammals can breathe through their anuses receive Ig Nobel prize kraken зеркало The world still holds many unanswered questions. But thanks to the efforts of the research teams awarded the IG Nobel Prize on Thursday some of these questions – which you might not even have thought existed – now have answers. We now know that many mammals can breathe through their anuses that there isn’t an equal probability that a coin will land on head or tails that some real plants somehow imitate the shapes of neighboring fake plastic plants that fake medicine which causes painful side-effects can be more effective than fake medicine without side-effects and that many of the people famous for reaching lofty old ages lived in places that had bad record-keeping. https://kraken3yvbvzmhytnrnuhsy772i6dfobofu652e27f5hx6y5cpj7rgyd.cc kraken3yvbvzmhytnrnuhsy772i6dfobofu652e27f5hx6y5cpj7rgyd onion The awards – which have no affiliation to the Nobel Prizes – aim to “celebrate the unusual honor the imaginative – and spur people’s interest in science medicine and technology” by making “people laugh then think.” In a two-hour ceremony as quirky as the scientific achievements it was celebrating audience members were welcomed to their seats by accordion music before a safety briefing warned them not to “sit on anyone unless you are a child” not to “feed chase or eat ducks” and to throw their paper airplane safely. There were two “paper airplane deluges” during the ceremony in which the audience attempted to throw their creations – safely – at a target in the middle of the stage. Among those collecting their prizes was a Japanese research team led by Ryo Okabe and Takanori Takebe who discovered that mammals can breathe through their anuses. They say in their paper that this potentially offers an alternative way of getting oxygen into critically ill patients if ventilator and artificial lung supplies run low like they did during the Covid-19 pandemic. American psychologist B.F Skinner was posthumously awarded the peace prize for his work attempting to use pigeons to guide the flight path of missiles while a European-wide research team was awarded the probability prize for conducting 350757 experiments to demonstrate that a coin tends to land on the same side it started when it is flipped.
Если вы искали где…
Если вы искали где отремонтировать сломаную технику, обратите внимание - <a href=https://krasnoyarsk.profi-teh-remont.ru>ремонт бытовой техники в красноярске</a>
Scientists who discovered…
Scientists who discovered mammals can breathe through their anuses receive Ig Nobel prize kra7 gl The world still holds many unanswered questions. But thanks to the efforts of the research teams awarded the IG Nobel Prize on Thursday some of these questions – which you might not even have thought existed – now have answers. We now know that many mammals can breathe through their anuses that there isn’t an equal probability that a coin will land on head or tails that some real plants somehow imitate the shapes of neighboring fake plastic plants that fake medicine which causes painful side-effects can be more effective than fake medicine without side-effects and that many of the people famous for reaching lofty old ages lived in places that had bad record-keeping. https://kraken3yvbvzmhytnrnuhsy772i6dfobofu652e27f5hx6y5cpj7rgyd.cc kra5 gl The awards – which have no affiliation to the Nobel Prizes – aim to “celebrate the unusual honor the imaginative – and spur people’s interest in science medicine and technology” by making “people laugh then think.” In a two-hour ceremony as quirky as the scientific achievements it was celebrating audience members were welcomed to their seats by accordion music before a safety briefing warned them not to “sit on anyone unless you are a child” not to “feed chase or eat ducks” and to throw their paper airplane safely. There were two “paper airplane deluges” during the ceremony in which the audience attempted to throw their creations – safely – at a target in the middle of the stage. Among those collecting their prizes was a Japanese research team led by Ryo Okabe and Takanori Takebe who discovered that mammals can breathe through their anuses. They say in their paper that this potentially offers an alternative way of getting oxygen into critically ill patients if ventilator and artificial lung supplies run low like they did during the Covid-19 pandemic. American psychologist B.F Skinner was posthumously awarded the peace prize for his work attempting to use pigeons to guide the flight path of missiles while a European-wide research team was awarded the probability prize for conducting 350757 experiments to demonstrate that a coin tends to land on the same side it started when it is flipped.
Long-lost copy of the US…
Long-lost copy of the US Constitution found in North Carolina filing cabinet heads to auction kra6.cc Historical document appraiser and collector Seth Kaller spreads a broad sheet of paper across a desk. It’s in good enough condition that he can handle it carefully with clean bare hands. There are just a few creases and tiny discolorations even though it’s just a few weeks shy of 237 years old and has spent who knows how long inside a filing cabinet in North Carolina. At the top of the first page are familiar words but in regular type instead of the sweeping Gothic script we’re used to seeing: “WE the People …” And the people will get a chance to bid for this copy of the US Constitution — the only of its type thought to be in private hands — at a sale by Brunk Auctions on Sept. 28 in Asheville North Carolina. https://kraken21at.net кракен ссылка The minimum bid for the auction of 1 million has already been made. There is no minimum price that must be reached. This copy was printed after the Constitutional Convention finished drafting the proposed framework of the nation’s government in 1787 and sent it to the Congress of the ineffective first American government under the Articles of Confederation requesting they send it to the states to be ratified by the people. It’s one of about 100 copies printed by the secretary of that Congress Charles Thomson. Just eight are known to still exist and the other seven are publicly owned.
Actress Gemma Arterton says…
Actress Gemma Arterton says director tried to pressure her to do sex scene kra4.gl British actress Gemma Arterton has revealed that a director once tried to put pressure on her to film a sex scene despite the fact that it wasn’t included in the script. In an interview with British publication the Radio Times released Tuesday Arterton said that whilst on set the director - who hasn’t been named - instructed her and her co-star to film a sex scene on a bed. “I said ‘No this scene was written for us to be off screen so you just hear the noises’” Arterton told the Radio Times. “I’d never have accepted the role if it was going to be filmed.” https://kra10gl.cc kra6.gl The actress said that she was pressured by the director to film the scene but that she “flat out” refused to take part in it. Had she been younger at the time Arterton suggested that she might have been more concerned about being fired for refusing to film it. “I only felt like I could say that because I was older” she said. “When I started acting there was a lot of nudity – you were just expected to do it. When I was younger I played sexy characters the girlfriend. As I’ve got older that’s changed because I’m more successful and can choose the parts I want to play” she said. She praised the use of intimacy coordinators in film and television since the #MeToo movement telling the magazine that “it’s a totally different landscape” now. “Anything you’re not comfortable with is not going to happen. I’ve heard other actors that are like ‘I loved it when there was no intimacy coordinator’ but I definitely think it’s better” she said.
Study shows how the pandemic…
Study shows how the pandemic may have affected teens’ brains kra13.gl The pandemic’s effects on teenagers were profound — numerous studies have documented reports of issues with their mental health social lives and more. Now a new study suggests those phenomena caused some adolescents’ brains to age much faster than they normally would — 4.2 years faster in girls and 1.4 years faster in boys on average according to the study published Monday in the journal Proceedings of the National Academy of Sciences. By being the first to contribute details on aging differences by sex the study adds to the existing body of knowledge provided by two previous studies on the Covid-19 pandemic and accelerated brain aging among adolescents. https://kra12gl.cc kra4 gl “The findings are an important wake-up call about the fragility of the teenage brain” said senior study author Dr. Patricia K. Kuhl the Bezos Family Foundation Endowed Chair in Early Childhood Learning and codirector of the Institute for Learning and Brain Sciences at the University of Washington in Seattle via email. “Teens need our support now more than ever.” Significant socioemotional development occurs during adolescence along with substantial changes to brain structure and function. The thickness of the cerebral cortex naturally peaks during childhood steadily decreases throughout adolescence and continues to decrease through one’s lifespan the authors wrote. The researchers originally intended to track ordinary adolescent brain development over time starting with MRIs the authors conducted on participants’ brains in 2018. They planned to follow up with them for another scan in 2020. The pandemic delayed the second MRI by three to four years — when the 130 participants based in Washington state were between ages 12 and 20. The authors excluded adolescents who had been diagnosed with a developmental or psychiatric disorder or who were taking psychotropic medications.
Meet the artist transforming…
Meet the artist transforming tennis balls into furniture bs2site.at In the last two years tennis has taken over our closets court-appropriate garb can be found everywhere from Skims to Miu Miu our screens who could forget Zendaya’s turn as the tennis protoge-turned-elite-coach Tashi Duncan in “Challengers” and now — our living rooms. At least that is the hope of Belgian eco-designer Mathilde Wittock who fashions bespoke furniture from discarded tennis balls. Wittock’s sleek modernist chaise longues are entirely cushionless — save for the padding of 500 precisely arranged tennis balls. Her one meter-long benches are similarly sparse with some 270 balls being both stylish and structurally substantial. https://blacksprutbs2best.net спрут “It takes around 24 different manufacturing steps to make a tennis ball which is around five days. Then it has such a short lifespan” Wittock told CNN in a video call from Brussels. “I was looking into tennis balls because I played tennis myself so I know there is a lot of waste.” Around 300 million tennis balls are produced each year — and almost all of them end up in landfills taking over 400 years to decompose. The US Open which ended at the weekend goes through around 70000 each year with Wimbledon not far behind at 55000. Wittock estimates the lifecycle of a ball stands at just nine games depending on the level of tennis being played. “Even if they are contained in their box if the box has been opened the gas inside the tennis balls will be released over time” she said. “Eventually they will get flat and you’ll have to throw them away.”
Summary Kamala Harris and…
Summary Kamala Harris and Donald Trump have had a fiery 90-minute debate in Philadelphia - their first of the 2024 US presidential election kra7.gl After shaking hands - it was the first time they had met - the pair debated policy before moving onto more personal attacks Harris said people leave Trump rallies early out of exhaustion and boredom - he said people dont go to hers in the first place kra8.cc https://kra06.gl Trump criticised Harriss record on immigration and the border and also her shifting policy positions - Harris blamed him for Trump abortion bans and for the 6 January attacks on the US Capitol Snap polls suggest Harris won the debate but Trump says afterwards that she lost very badly With the election taking place on 5 November Harris is slightly ahead in national opinion polls - but polls are very tight in key battleground states Shortly after the debate Taylor Swift endorsed Harris on Instagram calling her a gifted leader
Summary Kamala Harris and…
Summary Kamala Harris and Donald Trump have had a fiery 90-minute debate in Philadelphia - their first of the 2024 US presidential election kra8.gl After shaking hands - it was the first time they had met - the pair debated policy before moving onto more personal attacks Harris said people leave Trump rallies early out of exhaustion and boredom - he said people dont go to hers in the first place kra6.cc https://kraken6-gl.com Trump criticised Harriss record on immigration and the border and also her shifting policy positions - Harris blamed him for Trump abortion bans and for the 6 January attacks on the US Capitol Snap polls suggest Harris won the debate but Trump says afterwards that she lost very badly With the election taking place on 5 November Harris is slightly ahead in national opinion polls - but polls are very tight in key battleground states Shortly after the debate Taylor Swift endorsed Harris on Instagram calling her a gifted leader
Профессиональный сервисный…
Профессиональный сервисный центр по ремонту бытовой техники с выездом на дом.
Мы предлагаем: <a href=https://remont-byttekhniki-moskva.ru>ремонт крупногабаритной техники в москве</a>
Наши мастера оперативно устранят неисправности вашего устройства в сервисе или с выездом на дом!
National Park calls out …
National Park calls out ‘world changing’ impact of dropped Cheetos bag кракен магазин Plain water is the only thing visitors are allowed to consume inside the huge cavern at Carlsbad Caverns National Park in New Mexico. Cheetos are a no-go and the recent park visitor who dropped a bag full of them created a “huge impact” on the cave’s ecosystem the park said Friday in a Facebook post. “At the scale of human perspective a spilled snack bag may seem trivial but to the life of the cave it can be world changing” the park said in its post about the garbage found off-trail in the Big Room. https://kra6-gl.cc kra15.cc “The processed corn softened by the humidity of the cave formed the perfect environment to host microbial life and fungi. Cave crickets mites spiders and flies soon organize into a temporary food web dispersing the nutrients to the surrounding cave and formations. Molds spread higher up the nearby surfaces fruit die and stink. And the cycle continues.” The park said rangers spent 20 minutes carefully removing molds and foreign debris from surfaces inside the cave noting that while some members of the ecosystem that rose from the snacks were cave-dwellers “many of the microbial life and molds are not.” The post called that particular impact on the cave “completely avoidable” contrasting it with the hard-to-prevent fine trails of lint left by each visitor. “Great or small we all leave an impact wherever we go. Let us all leave the world a better place than we found it” the post urged park goers. The park’s website says that eating and drinking anything other than plain water attracts animals into the cavern. Carlsbad Caverns followed up its post about the Cheetos bag with a post about the “leave no trace” principle of disposing of waste properly. “Contrary to popular belief the cave is NOT a big trash can” the post said yet rangers pick up waste left behind every day. “Sometimes this can be a gum wrapper or a tissue other times it can unfortunately mean human waste spit or chewing tobacco.” Visitors are asked to make sure they don’t leave trash in the cavern and to use designated restrooms.
Если вы искали где…
Если вы искали где отремонтировать сломаную технику, обратите внимание - <a href=https://nizhniy-novgorod.profi-teh-remont.ru>сервис центр в нижнем новгороде</a>
The world’s best pizza for…
The world’s best pizza for 2024 isn’t in Naples – or even in Italy. Here’s where it is … kraken5af44k24fwzohe6fvqfgxfsee4lgydb3ayzkfhlzqhuwlo33ad Many New Yorkers will gladly tell anyone who’ll listen – and even those who won’t – about how they have the best pizza. And now they’ve got some mouth-watering new back-up for their long-standing culinary claims. This week the Italy-based 50 Top Pizza Awards came out with its 2024 worldwide list and a Lower East Side restaurant came out on top. Una Pizza Napoletana opened by pizza maestro Anthony Mangieri in March 2022 not only beat out US competitors but also global ones. That includes pizzerias in Naples Italy the holy land for pizza aficionados and foodies in general. “It’s inspiring to be recognized for this 30 years into my career especially in Naples where pizza originated” Mangieri said in an email to CNN Travel on Thursday. https://kraken2trfqodidvlh4aa337cpzfrhdlfldhve5nf7njhumwr7insta.cc kraken6gf6o4rxewycqwjgfchzgxyfeoj5xafqbfm4vgvyaig2vmxvyd Adding to their bragging rights New Yorkers saw three other pizzerias make the 2024 list which included 101 restaurants in total despite the “50” in the name of the awards. The rankings for the other New York pizzerias were Ribalta at No. 19 Don Antonio at No. 30 and L’industrie Pizzeria at No. 80. Italy still managed to dominate the overall list with 41 eateries while the United States got a total of 15 places recognized. And Naples managed to best New York with five entries on the list including a tie for the No. 2 spot with Diego Vigtaliano Pizzeria. Showing how truly global the awards are nations not exactly known for their pizza scenes –South Korea Bolivia and India to name three – were represented on the list.
url=https:/…
url=https://rentyachtsincyprus.com/yacht charter cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/Yacht charter Cyprus/url url=https://rentyachtsincyprus.com/Yacht charter Cyprus/url url=https://rentyachtsincyprus.com/enYacht charter Cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/Yacht charter Cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/yacht charter cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/yacht charter cyprus/url url=https://rentyachtsincyprus.com/yacht charter cyprus/url url=https://rentyachtsincyprus.com/enYacht charter Cyprus/url url=https://rentyachtsincyprus.com/yacht charter cyprus/url url=https://rentyachtsincyprus.com/enYacht charter Cyprus/url url=https://rentyachtsincyprus.com/yacht charter cyprus/url url=https://rentyachtsincyprus.com/enYacht charter Cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url
Yacht charter Cyprus yacht…
Yacht charter Cyprus yacht charter cyprus yacht charter cyprus Yacht charter Cyprus Yacht charter Cyprus yacht charter cyprus yacht charter cyprus yacht charter cyprus Yacht charter Cyprus Yacht charter Cyprus Yacht charter Cyprus Yacht charter Cyprus Yacht charter Cyprus Yacht charter Cyprus yacht charter cyprus Yacht charter Cyprus yacht charter cyprus yacht charter cyprus yacht charter cyprus
Yacht charter Cyprus yacht…
Yacht charter Cyprus yacht charter cyprus Yacht charter Cyprus Yacht charter Cyprus Yacht charter Cyprus Yacht charter Cyprus yacht charter cyprus yacht charter cyprus yacht charter cyprus yacht charter cyprus Yacht charter Cyprus Yacht charter Cyprus Yacht charter Cyprus Yacht charter Cyprus Yacht charter Cyprus yacht charter cyprus yacht charter cyprus yacht charter cyprus Yacht charter Cyprus
url=https:/…
url=https://rentyachtsincyprus.com/Yacht charter Cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/Yacht charter Cyprus/url url=https://rentyachtsincyprus.com/Yacht charter Cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/enYacht charter Cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/enYacht charter Cyprus/url url=https://rentyachtsincyprus.com/enYacht charter Cyprus/url url=https://rentyachtsincyprus.com/yacht charter cyprus/url url=https://rentyachtsincyprus.com/enYacht charter Cyprus/url url=https://rentyachtsincyprus.com/yacht charter cyprus/url url=https://rentyachtsincyprus.com/yacht charter cyprus/url url=https://rentyachtsincyprus.com/enYacht charter Cyprus/url url=https://rentyachtsincyprus.com/yacht charter cyprus/url url=https://rentyachtsincyprus.com/yacht charter cyprus/url
url=https:/…
url=https://rentyachtsincyprus.com/Yacht charter Cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/enYacht charter Cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/Yacht charter Cyprus/url url=https://rentyachtsincyprus.com/yacht charter cyprus/url url=https://rentyachtsincyprus.com/yacht charter cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/yacht charter cyprus/url url=https://rentyachtsincyprus.com/enYacht charter Cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/Yacht charter Cyprus/url url=https://rentyachtsincyprus.com/Yacht charter Cyprus/url url=https://rentyachtsincyprus.com/yacht charter cyprus/url url=https://rentyachtsincyprus.com/enyacht charter cyprus/url url=https://rentyachtsincyprus.com/Yacht charter Cyprus/url url=https://rentyachtsincyprus.com/yacht charter cyprus/url url=https://rentyachtsincyprus.com/enYacht charter Cyprus/url
Yeni yorum ekle